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目的:探讨盐酸氨溴索所致不良反应(ADR)的情况,为临床用药提供帮助,以指导临床合理用药。方法:收集使用盐酸氨溴索发生药物不良反应28例病例进行统计分析。结果:发生不良反应的28例中,首次使用即发生症状者22例(78.57%),连续用药2次以上才发生ADR的6例(21.43%)。症状最早出现者为首次使用后10分钟内,最迟时间发生在首次用药后4天。男性发生ADR13例(46.43%),女性发生ADR15例(53.57%)。口服发生5例(17.86%),静脉给药发生23例(82.14%)。结论:临床用药中应注意盐酸氨溴索的不良反应,早发现,及时处理。
Objective: To investigate the adverse reactions caused by Ambroxol Hydrochloride (ADR), to provide help for the clinical use of drugs to guide clinical rational use of drugs. Methods: A total of 28 cases of adverse reactions of ambroxol hydrochloride were collected for statistical analysis. Results: Of the 28 patients who developed adverse reactions, 22 (78.57%) were those who had symptoms for the first time and 6 (21.43%) were ADRs after 2 or more consecutive doses of ADR. The earliest symptoms were within 10 minutes after the first use, and the latest occurred 4 days after the first dose. There were 13 cases (46.43%) of ADRs in men and 15 cases (53.57%) of ADRs in women. Oral cases occurred in 5 cases (17.86%), intravenous administration occurred in 23 cases (82.14%). Conclusion: The adverse reactions of Ambroxol Hydrochloride should be noticed in the clinical medication, which should be detected and treated promptly.