最近Baker&Ross(1980)报道了第一例放疗后声门上水肿所致的阻塞性睡眠呼吸暂停综合征。作者们治疗了第二例具有类似病史和治疗效果的病例,并描述了对该综合征的简单诊断法。患者男性,57岁,为评价其睡眠而入院。5年前,患舌根部低分化鳞癌,行放射治疗。此后肿瘤无明显复发,但有严重的固体饮食咽下困难和间歇性声嘶,并有全身乏力和嗜睡。近来病人感自主活动困难、流涎和说话时有窒息性语音,下颌开大不到3cm,颈部触诊变硬。病人谈话终止时即刻睡着,显示有上呼吸道阻塞型呼吸暂停。肺功能试验正常,肺流量图诊断为可变的胸外阻塞。颈侧位X线照片及喉断层相显示严重的咽食管隙变窄继发于脊柱前软组织肿胀和显著的声门上肿胀,杓会厌襞及梨状窝亦肿胀。综合上 Recently Baker & Ross (1980) reported the first obstructive sleep apnea syndrome caused by supraglottic edema after radiotherapy. The authors treated a second case with similar medical history and treatment, and described a simple diagnosis of the syndrome. Male, 57, admitted to hospital for evaluation of sleep. 5 years ago, suffering from poorly differentiated squamous cell carcinoma of the tongue, radiation therapy. Since then no significant tumor recurrence, but severe solid diet swallowing difficulties and intermittent hoarseness, and generalized fatigue and lethargy. Recently, patients with autonomy activity difficulties, salivation and speech asphyxiation voice, mandibular open less than 3cm, neck palpation hard. The patient fell asleep immediately after the conversation was terminated, showing upper airway obstruction apnea. Pulmonary function tests were normal, and pulmonary flow maps were diagnosed as variable extrathoracic occlusions. Lateral neck radiographs and laryngeal facies show severe pharyngeal esophageal space narrowing secondary to swelling of the soft tissue of the spine and significant swelling of the supraglottic tract, scrotum epiglottis and piriformis also swollen. Comprehensive