新型隐球菌侵犯中枢神经系统最常见的症状和体征是脑膜炎、脑膜脑炎或占位性损害。头痛伴颈项强直、视乳突水肿、进行性局灶征是本病最常见的特征。突起轻偏瘫作为隐球菌脑膜脑炎表现的体征是罕见的。文献中仅有一例报告。本文报告为第二例,系继发于脉管炎的右大脑中动脉半球小分支突然闭塞或右内囊的分支的脓毒性栓塞。患者男性,36岁。当9个月以来隐袭出现头痛后,需定期使用止痛剂。住院前2周头痛加剧,住院前一天,突起左手不能放到计算器键盘上,左下肢麻木,语言含糊不清。当地医院检查:精神状态正常,左侧轻瘫,左侧反射亢进,左侧巴彬斯基征阳性,感觉正常。头部CT 扫描正常。腰椎穿刺检 The most common symptoms and signs of Cryptococcus neoformans invasion of the central nervous system are meningitis, meningoencephalitis or lesions. Headache with neck stiffness, papilloma edema, progressive focal signs are the most common features of the disease. Herniated hemiparesis is rare as a manifestation of cryptococcal meningoencephalitis. There is only one report in the literature. This article reports as a second case of a septic embolism with a sudden occlusion of the small branch of the right middle cerebral artery secondary to vasculitis or a branch of the right internal capsule. Male patient, 36 years old. Painkillers need to be regularly administered after a headache for nine months. Headache increased 2 weeks before hospitalization, the day before hospitalization, protruding left hand can not be placed on the calculator keyboard, left lower limb numbness, vague language. Local hospital examination: mental state is normal, left paralysis, left hypersensitivity, left Babinski sign positive, feeling normal. Head CT scan is normal. Lumbar puncture seizure