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目的探讨软脑膜转移癌的病因、影像学特征、治疗方法以及临床转归,为临床上进一步认识该病提供一些资料。方法总结我科近年来收治的典型软脑膜转移癌病例8例,包括临床表现、头部CT和MRI等影像学资料、脑脊液细胞学和病理活检结果、临床治疗效果的对比等。结果8例病人均证实有恶性肿瘤转移至颅内软脑膜部位,增强MRI检查有特征性的表现,腰穿脑脊液细胞学检查阳性率较高,可达到85%～90%。结论软脑膜转移癌病人预后差,如能早期作出诊断并给予适当的治疗,可以延长病人的生存期。
Objective To explore the etiology, imaging features, treatment and clinical outcome of piamania metastatic cancer and to provide some information for further understanding of the disease. Methods Eight cases of typical pia mater metastatic carcinoma treated in our department in recent years were summarized, including clinical manifestations, imaging data of head CT and MRI, cytological and pathological biopsy results of cerebrospinal fluid and the comparison of clinical therapeutic effects. Results Eight patients all had malignant tumor metastasized to intracranial leptomeniocentesis and enhanced MRI examination showed characteristic features. The positive rate of lumbar puncture cerebrospinal fluid cytology was 85% -90%. Conclusions The prognosis of patients with PTSD is poor. Patients who have early diagnosis and proper treatment can prolong their survival.