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目的探讨胃原发性非霍奇金淋巴瘤(NHL)临床表现特点、诊断及治疗方式,提高对本病的认识。方法我院2001年1月—2011年1月收治的35例确诊为胃原发性NHL进行回顾性分析患者的临床表现,诊断及治疗方法。结果胃原发性NHL的临床表现缺乏特异性,X线误诊率高,35例患者均行胃镜或X线造影仅16例确诊,诊断率仅45.7%。16例根治术+化疗或放疗5年生存率达93%,姑息性手术+化疗或放疗5年生存率为75%。结论熟悉胃原发性NHL的临床特点,通过X线检查、内窥镜多次多处取点检查,提高对本病的认识,降低误诊率。采用以手术为主,术后辅助化疗和/或放疗的综合性治疗可提高患者生存率。了解影响本病预后的因素与临床病理分期及治疗方法。
Objective To investigate the clinical features, diagnosis, and treatment of primary non-Hodgkin lymphoma (NHL) in the stomach and improve the understanding of this disease. METHODS: The clinical manifestations, diagnosis and treatment of 35 patients diagnosed as primary NHL in the hospital from January 2001 to January 2011 were retrospectively analyzed. Results The clinical manifestations of primary NHL were lack of specificity, and the misdiagnosis rate of X-ray was high. All the 35 patients underwent gastroscopy or X-ray angiography only in 16 cases. The diagnosis rate was only 45.7%. The 5-year survival rate of radical mastectomy + chemotherapy or radiotherapy was 93%, and the 5-year survival rate of palliative surgery + chemotherapy or radiotherapy was 75%. Conclusions To be familiar with the clinical features of primary NHL in the stomach, to improve the understanding of the disease and reduce the misdiagnosis rate through X-ray examination and multiple endoscopic examinations. The use of surgery-based, postoperative adjuvant chemotherapy and/or radiation therapy can improve patient survival. Understand the factors affecting the prognosis of the disease and clinical pathological staging and treatment methods.