本文通过病例介绍简述铅对周围神经损害的临床特征及职业性铅接触者、尤其是尚无临床表现的铅接触者的神经电生理和神经病理。其中,部分肌电图显示异常、神经传导速度减慢和神经病理改变。已有结果表明,肌电图和神经传导速度与血铅水平之间存在接触水平-效应/反应关系,并期望通过这种关系来得到无效应-反应水平的血铅水平,从而为确定铅中毒的阈限值及制定中毒诊断标准提供客观依据。 This article presents a brief description of the clinical features of lead exposure to peripheral nerves and the electrophysiological and neuropathological findings of occupational lead exposures, especially those not yet clinically exposed. Among them, some EMG showed abnormalities, nerve conduction slowed and neuropathological changes. It has been shown that there is a contact level-effect / response relationship between electromyography and nerve conduction velocity and blood lead levels, and it is expected that blood lead levels with no effect-response level can be obtained through this relationship, so as to determine lead poisoning The threshold limits and the development of diagnostic criteria to provide an objective basis for poisoning.