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目的:探讨nt-bnp在诊断心衰合并慢性肾功能不全疾病中的临床意义。方法:选择我院收治的心衰合并慢性肾功能不全的患者200例,作为试验组;选择心衰患者200例,作为对照组A,另外选取同期健康体检者200例作为对照组B。运用微粒子捕捉免疫化学发光法,分别检测三组患者的血浆nt-bnp水平,并比较三组患者该指标的差异。结果:经过检测,试验组和对照组A nt-bnp水平均明显高于对照组B,而试验组nt-bnp水平要高于对照组A,试验组不同等级的心功能患者nt-bnp水平均高于对照组,且随心功能级别增高而明显增高,与心功能级别成正比。结论:nt-bnp可以作为心衰合并慢性肾功能不全疾病的重要诊断指标,临床意义重大,值得推广应用。
Objective: To investigate the clinical significance of nt-bnp in the diagnosis of heart failure complicated with chronic renal insufficiency. Methods: 200 patients with heart failure and chronic renal insufficiency admitted to our hospital were selected as the experimental group. 200 patients with heart failure were selected as the control group A, and 200 healthy subjects were selected as the control group B in the same period. The use of particle capture immuno-chemiluminescence method were detected in three groups of patients with plasma nt-bnp levels, and compared the differences in the three groups of patients. Results: After the test, the A nt-bnp level of the experimental group and the control group was significantly higher than that of the control group B, while the level of nt-bnp in the experimental group was higher than that of the control group A. The levels of nt-bnp in different grades of cardiac function test group Higher than the control group, and increased with the level of cardiac function was significantly higher, and is proportional to the level of cardiac function. Conclusion: nt-bnp can be used as an important diagnostic indicator of heart failure complicated with chronic renal insufficiency. It is of great clinical significance and should be popularized and applied.