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[目的]分析2002～2004年上海市0～14岁儿童恶性肿瘤的流行病学特征。[方法]利用上海市肿瘤登记报告和随访管理系统收集的儿童恶性肿瘤发病资料,开展回顾性调查工作,包括病史摘录、病例报告卡和死亡单核对等。采用国际儿童肿瘤分类系统(ICCC)进行归类分析。[结果]2002～2004年,上海市新诊断儿童恶性肿瘤病例447例,粗发病率为112.5/100万,标化发病率为120.3/100万。男、女性儿童恶性肿瘤发病率接近,标化发病率分别为118.2/100万和122.6/100万。不同年龄组发病率不同,0～4岁组发病率最高,发病率达148.7/100万。白血病是最常见的儿童恶性肿瘤,约占全部病例的三分之一(30.9%),主要为淋巴细胞白血病(66.7%)。CNS肿瘤为第2位常见肿瘤(21.9%),其次为淋巴瘤(9.6%)。[结论]上海市儿童恶性肿瘤发病率较西方国家低,主要瘤别分布一致,不同性别和年龄别发病率不同。为进一步开展儿童恶性肿瘤病因和预后研究提供基础数据。
[Objective] To analyze the epidemiological characteristics of malignant tumors in children aged 0-14 in Shanghai from 2002 to 2004. [Methods] The retrospective investigation was carried out on the incidence of childhood malignant tumors collected by Shanghai Tumor Registry and Follow-Up Management System, including the excerpts of history, case report card and single-check of death. Using the International Classification of Children’s Tumors (ICCC) for classification analysis. [Results] From 2002 to 2004, 447 newly diagnosed cases of childhood malignancies were diagnosed in Shanghai. The crude incidence rate was 112.5 / 1 million and the standardized incidence rate was 120.3 / 1 million. The incidence rates of malignant tumors in male and female children were close to those of normal subjects, with the incidence rates of 118.2 / 1 million and 122.6 / 1 million respectively. The incidence of different age groups is different, the highest incidence of 0 to 4 years old group, the incidence rate of 148.7 / 1 million. Leukemia is the most common childhood malignancy, accounting for about one third (30.9%) of all cases, mainly lymphocytic leukemia (66.7%). CNS tumor was the second most common tumor (21.9%), followed by lymphoma (9.6%). [Conclusion] The incidence of malignant tumors in children in Shanghai is lower than that in western countries. The distribution of major tumors is the same, and the incidence rates are different for different sexes and ages. To further carry out the etiology and prognosis of children with malignant tumors provide the basic data.