A physical model based on similarity principles was built to simulate RH desulfurization process.In order to quantitatively analyze RH desulfurization process,a mathematical model was proposed.By analyzing experimental results with the mathematical model,an empirical formula whose determination coefficient was 0.98 was given to express the relationship between transient desulfurization efficiency and time.All the determination coefficients of four fitted curves based on four repeated experiments with different gas flow rates were more than 0.94,which was the exact evidence of the rationality of the empirical formula.Meanwhile,it was found that transient desulfurization ability increased firstly and then decreased with increasing gas flow rate and reached the maximum value when the gas flow rate was 1.8m3/h.A plenty of repeated trials showed the same rule,which validated the mathematical model and the conclusions obtained from physical experiments. A physical model based on similarity principles was built to simulate RH desulfurization process. In order to quantitatively analyze RH desulfurization process, a mathematical model was proposed. By analyzing the experimental model with an mathematical model, an empirical formula was 0.98 was given to express the relationship between transient desulfurization efficiency and time. All the determination coefficients of four fitted curves based on four repeated experiments with different gas flow rates were more than 0.94, which was the exact evidence of the rationality of the empirical formula. found that transient desulfurization ability increased first and then decreased with increasing gas flow rate and reached the maximum value when the gas flow rate was 1.8m3 / hA plenty of repeated trials showed the same rule, which validated the mathematical model and theologically obtained from physical experiments.