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在正常人尿中每天排出Tamm-Horsfall(TH)糖蛋白可达100mg。它除了致密斑,可由亨氏袢升支的小管上皮细胞和远曲小管直至集合管起始部的浆细胞产生。TH是透明管型的主要成分。1962年McQueen提出严重蛋白尿的病人TH排出量比正常人增加。1964年Mckenzie等提出在肾病综合征患者中尿蛋白排出的变化与TH排出的变化成平行,肌酐清除率和TH排出率间成正相关本文研究了各种肾病组中影响TH排出的某些因素。病人和方法 100例病人进行了肾脏疾病的检查,除2例年青者后来发现肾脏正常外,共为98例(55例男,43例
Tamm-Horsfall (TH) glycoprotein is excreted as much as 100 mg daily in normal human urine. In addition to its dense plaque, it can be Hepburn ascending branch of the tubular epithelial cells and distal convoluted tubules until the beginning of the collection tube plasma cells. TH is the main component of transparent tube. 1962 McQueen put forward serious cases of proteinuria in patients with TH excretion than normal. Mckenzie et al. Proposed in 1964 that changes in urinary protein excretion in patients with nephrotic syndrome be parallel to changes in TH excretion, and that there was a positive correlation between creatinine clearance and TH excretion. Several factors affecting TH excretion in various nephrotic groups were studied. Patients and Methods A total of 98 patients (55 men and 43 women) were examined for kidney disease in 100 patients, except for 2 young patients who later found their kidneys normal.