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目的应用还原型谷胱甘肽(GSH)治疗慢性乙型肝炎64例,以评价其疗效。方法治疗组在常规综合基础治疗的基础上,加用GSH1.8g溶于10%葡萄糖250ml中静脉滴注,每日1次,持续1个月,对照组用常规综合基础治疗,以肝功能及有效率作为判断疗效的指标。结果治疗组谷丙转氨酶(ALT)和血清总胆红素(SB)治疗后与对照组相比有显著差异(P<0.05),且其总有效率达94%,较对照组总有效率75%有显著意义。结论应用GSH治疗慢性乙型肝炎安全、有效。
Objective To evaluate the efficacy of reducing glutathione (GSH) in the treatment of 64 chronic hepatitis B patients. Methods On the basis of conventional comprehensive basic treatment, the treatment group was treated with intravenous infusion of GSH1.8g dissolved in 250ml of 10% glucose for 1 month, and the control group was treated with conventional comprehensive basic therapy. The liver function and Efficacy as an indicator of efficacy. Results There was a significant difference (P <0.05) between the treatment group and the control group after treatment of ALT and SB, and the total effective rate was 94%, which was 75% higher than that of the control group % Is significant. Conclusion The application of GSH in the treatment of chronic hepatitis B is safe and effective.