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目的探讨双石汤与松龄血脉康治疗原发性高血压患者的临床疗效。方法选取2014年1月至2015年12月甘肃省庄浪县中医医院收治的原发性高血压患者100例作为研究对象,将其采用随机数字表法分为对照组和试验组,各50例。对照组患者给予松龄血脉康胶囊,试验组患者采用双石汤进行治疗,比较两组患者治疗前后血压、血脂水平变化情况,并评估降压疗效和中医证候积分。结果治疗后,两组患者的收缩压、舒张压均明显低于治疗前,差异均有统计学意义(均P<0.05),但组间比较差异均无统计学意义(均P>0.05);试验组患者的中医证候积分明显低于对照组,差异有统计学意义(P<0.05);试验组患者中医症候疗效明显高于对照组,差异有统计学意义(P<0.05);治疗后,试验组患者的总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)水平均明显低于对照组,高密度脂蛋白胆固醇(HDL-C)水平明显高于对照组,差异均有统计学意义(均P<0.05)。结论双石汤及松龄血脉康治疗原发性高血压均有良好的降压效果,但双石汤有利于改善患者血脂水平,中医症候疗效更为显著。
Objective To investigate the clinical efficacy of Shoushi Decoction and Songling Xuemaikang in the treatment of patients with essential hypertension. Methods A total of 100 patients with essential hypertension admitted to Zhuanglang Hospital of Traditional Chinese Medicine in Gansu Province from January 2014 to December 2015 were selected as study subjects and divided into control group and trial group by random number table . Patients in the control group were treated with Songlingximaikang capsule. Patients in the test group were treated with Shuangshi Decoction. The changes of blood pressure and blood lipid level before and after treatment were compared between the two groups. Blood pressure-lowering efficacy and TCM syndrome score were also evaluated. Results After treatment, systolic blood pressure and diastolic blood pressure in both groups were significantly lower than those before treatment (all P <0.05), but there was no significant difference between the two groups (all P> 0.05). The scores of TCM syndromes in the experimental group were significantly lower than those in the control group (P <0.05). The curative effect of TCM symptoms in the experimental group was significantly higher than that in the control group (P <0.05) (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) in the experimental group were significantly lower than those in the control group, and the levels of high-density lipoprotein cholesterol (HDL-C) Control group, the differences were statistically significant (P <0.05). Conclusion Shuangshi Decoction and Songling Xuemaikang have good antihypertensive efficacy in treating essential hypertension. However, Shuangshi Decoction can improve the level of blood lipids in patients with TCM syndrome.