幽门螺杆菌(Helicobacter pylori,HP)是B型胃炎的主要病因,并与十二指肠溃疡复发有关。细菌培养虽可用以确诊HP,但耗时长久。而快速尿素酶试验与细胞学检查可很快得到结果。本文研究了印片细胞学对HP诊断的敏感性和可重复性,并首次在同一标本对不同的诊断HP的方法进行了比较。病人和方法研究对象为做纤维胃镜检查的19例十二指肠溃疡患者。每个病人均于胃体、胃窦和十二指肠球部三个部位的溃疡边缘各取4块活检组织,前两块用于细胞学检查和培养,后两块用于印片细胞学和组织学检查。鉴于印片可能对活检的质量及其细菌数量有影 Helicobacter pylori (HP) is the main cause of B-type gastritis and is related to the recurrence of duodenal ulcer. Although bacterial culture can be used to confirm the HP, but time-consuming. Rapid urease test and cytology can get results quickly. This article studies the sensitivity and reproducibility of print cytology for the diagnosis of HP, and for the first time in the same specimen different HP diagnostic methods were compared. Patients and Methods Subjects were 19 patients with duodenal ulcer who underwent endoscopy. Each patient in the gastric body, gastric antrum and duodenal bulb at the three parts of the ulcer edge of each take 4 biopsies, the first two for cytological examination and culture, the latter two for printing cytology And histological examination. Given that the print may have a bearing on the quality of the biopsy and its bacterial population