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背景：应用超声骨密度仪检测骨密度缺乏定量超声独立使用的临床指征标准。 目的：了解深圳地区13～15岁不同性别少年超声骨密度状况；建立该年龄段少年超声骨密度正常参考值。 设计：横断面调查。 单位：深圳市龙岗区人民医院超声科。 对象：选择2003-04-12深圳市二所中学的13～15岁学生健康志愿者158例，排除曾发生骨折者和6个月内服用激素等影响骨代谢药物者，男90例，女68例。女性分为无月经初潮组和有月经初潮组。 方法：采用美国SAHARA超声骨密度仪，开机后用标准体模校正通过(精确性误差<1％，准确性误差为3％)，测定所有受试者左足跟骨密度值(g／cm~2)，足跟置于探头间，用定位附件调节固定位置，用同一身高、体重计，测量所有受检者的体质量(kg)、身高(cm)。 主要观察指标：①13～15岁正常少年身高、体质量及跟骨骨密度测量结果。②13～15岁不同性别的正常少年骨密度测量结果。③13～15岁正常女性无月经初潮者和有月经初潮者骨密度分布。 结果：①13～15岁正常少年身高、体质量及跟骨骨密度测量结果：14岁身高增长速度是15岁少年的2倍多(4．705cm／年，2．096cm／年)，骨密度的平均增长率14岁较13岁为负增长，15岁较14岁增长10．8％；体质量与骨密度呈正相关性(γ=0．820，P<0．01)。②13～15岁不同性别的正常少年骨密度测量结果：女性高于男性[13岁(0．542±0．117)比(0．528±0．086)g／cm~2，14岁(0．508±0．108)比(0．487±0．079)g／cm~2，15岁(0．609±0．234)比(0．501±0．225)g／cm~2]③13～15岁正常女性无月经初潮者和有月经初潮者骨密度分布：有月经初潮者高于无月经初潮者(P<0．001)。 结论：①13～15岁少年足跟部骨密度与性别和身高增长快慢有关。②体质量对骨密度的影响比身高对骨密度的影响大。③有月经初潮女性因雌激素增加有促进骨密度增高作用。
Background: The clinical indication criteria for the use of ultrasound bone densitometry in the measurement of bone mineral density lack of quantitative ultrasound. OBJECTIVE: To understand the status of ultrasound bone density in different age groups of 13 ~ 15 years old in Shenzhen, and to establish the normal reference value of ultrasound bone mineral density in this age group. Design: Cross-sectional survey. Unit: Longgang District People’s Hospital of Shenzhen ultrasound. PARTICIPANTS: A total of 158 healthy volunteers aged 13 to 15 years old from two middle schools in Shenzhen City were enrolled in the study. Among them, 90 were male and 68 were female, excluding those who had fractures and those who took hormone for 6 months. example. Women were divided into no menarche group and menarche group. Methods: SAHARA ultrasonic bone densitometer was used in the United States. After starting up, it was calibrated with standard phantom (accuracy error <1%, accuracy error 3%), and the left calcaneal bone mineral density (g / cm ~ ), The heel placed between the probe, with the positioning attachment to adjust the fixed position, with the same height, weight meter, measuring all subjects weight (kg), height (cm). MAIN OUTCOME MEASURES: ① The height, body mass and calcaneal bone mineral density of 13 ~ 15-year-old normal boys were measured. ②13-year-old 15-year-old boys and girls of different genders measured the results of normal bone mineral density. ③13-year-old 15-year-old normal men and women without menarche and menarche were bone mineral density distribution. Results: (1) The height, body weight and calcaneal bone density of normal young people aged from 13 to 15 were higher than those of 15-year old (4.705cm / year, 2.096cm / year) The average growth rate was negative at 14 years old compared with 13 years old, and 10.8% at 15 years old. The body weight was positively correlated with BMD (γ = 0.820, P <0.01). (2) The measurements of bone mineral density in normal teenagers aged from 13 to 15 years were higher than those in females (0.542 ± 0.117 vs 0.528 ± 0.086g / cm 2, 14years old .508 ± 0.108) (0.487 ± 0.079) g / cm ~ 2,15 (0.609 ± 0.234) vs (0.501 ± 0.225) g / cm ~ 2] (3) The distribution of BMD in normal women aged from 13 to 15 years without menarche or with menarche was higher than those without menarche (P <0.001). Conclusion: ① The heel bone density of 13 ~ 15 years old is related to the growth of gender and height. ② body mass impact on bone mineral density than the height of bone density. ③ women with menarche due to increased estrogen to promote bone mineral density increased role.