论文部分内容阅读
目的探讨原发性肾上腺弥漫性大B细胞淋巴瘤的临床特征。方法分析3例原发性肾上腺弥漫性大B细胞淋巴瘤病例资料,并进行组织形态学观察和免疫组织化学检测。结果3例患者诊断为原发性肾上腺弥漫性大B细胞淋巴瘤,临床上无特异性,1例患者死亡,2例术后行化疗或化疗联合放疗后病情好转。结论原发性肾上腺弥漫性大B细胞淋巴瘤是一种罕见的、恶性程度较高的肿瘤,诊断依赖于组织病理学及免疫组织化学标记检查。术前确诊肾上腺原发性非霍奇金淋巴瘤可避免手术,联合化疗应为治疗首选。
Objective To investigate the clinical features of primary adrenal diffuse large B cell lymphoma. Methods The data of 3 cases of primary adrenal diffuse large B-cell lymphoma were analyzed and the histopathological observation and immunohistochemistry were performed. Results Three patients were diagnosed as primary adrenal diffuse large B-cell lymphoma, which was clinically nonspecific. One patient died and two patients recovered after chemotherapy or chemotherapy combined with radiotherapy. Conclusions Primary adrenal diffuse large B-cell lymphoma is a rare and highly malignant tumor whose diagnosis depends on histopathology and immunohistochemistry. Preoperative diagnosis of adrenal non-Hodgkin’s lymphoma can avoid surgery, combined chemotherapy should be the treatment of choice.