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目的探讨乙肝患者HBV-LP与HBV-DNA表达的相关性,分析其临床诊断价值。方法选择本院2013年1月至2013年10月确诊为乙肝的70例患者作为观察组,另选择同期50例健康人群作为对照组,在相同条件下抽取静脉血进行血清检测,检测方法采用酶联免疫吸附试验法(ELISA),观察指标为HBV-LP和HBV-DNA,比较两组差异性。结果观察组HBV-LP阳性率高,HBV-DNA拷贝数高,与HBV-LP呈正相关,与对照组比较,两者比较差异具有显著性。结论乙肝患者HBVDNA复制明显,血清HBV-LP检测可以作为重要的临床诊断指标。
Objective To investigate the correlation between the expression of HBV-LP and HBV-DNA in patients with hepatitis B and to analyze its clinical value. Methods Seventy patients diagnosed with hepatitis B from January 2013 to October 2013 in our hospital were selected as the observation group. Another 50 healthy people were selected as the control group during the same period. Blood samples were drawn from the venous blood under the same conditions. The detection method used enzyme Immunoadsorption assay (ELISA), the indicators for the HBV-LP and HBV-DNA, the two groups were compared. Results The positive rate of HBV-LP in the observation group was high, the copy number of HBV-DNA was high, and it was positively correlated with HBV-LP. Compared with the control group, the difference was significant. Conclusion HBVDNA replication in patients with hepatitis B is obvious, serum HBV-LP test can be used as an important clinical diagnostic indicators.