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目的:探讨青春期多囊卵巢综合征(PCOS)的个体化治疗方法。方法:2008年1月～2011年12月就诊于该中心确诊为青春期PCOS患者,总计146例,按不同临床症状、体征分6组,每组给予个体化治疗,比较每组治疗前后效果。结果:各组患者治疗前和治疗后3个月比较,月经异常、痊疮、体重指数、腰臀比、糖耐量实验(OGTT)、焦虑情况均有不同程度的改善,两组间比较差异有统计学意义(P<0.05或P<0.01);多毛症状有改善,但组间比较差异无统计学意义(P>0.05)。结论:根据临床症状及体征将患者分类,针对不同病情给予个体化治疗方案,安全有效,利于患者接受,值得推广应用。
Objective: To explore the individualized treatment of adolescent polycystic ovary syndrome (PCOS). Methods: From January 2008 to December 2011, a total of 146 PCOS patients diagnosed as adolescent were admitted to this center. Six patients were divided into six groups according to different clinical symptoms and signs. Individualized treatment was given in each group. The effect of each group was compared before and after treatment. Results: Before treatment and 3 months after treatment, abnormal menstruation, heal ulcer, body mass index, waist-hip ratio, glucose tolerance test (OGTT) and anxiety were all improved to some extent. There was significant difference between the two groups Statistical significance (P <0.05 or P <0.01); Humor symptoms improved, but there was no significant difference between the two groups (P> 0.05). Conclusion: According to the clinical symptoms and signs of the patients were classified for different conditions given individualized treatment programs, safe and effective, conducive to patient acceptance, it is worth to promote the application.