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目的:探讨中药联合沙利度胺治疗多发性骨髓瘤(MM)的临床疗效。方法:抽选98例MM患者,采用随机数字表法分为对照组(n=49例,采用常规VAD方案化疗)和观察组(n=49例,在对照组基础上加服中药联合沙利度胺),比较两组治疗效果。结果:观察组患者骨痛评分、肿瘤负荷指标等改善情况明显优于对照组(P<0.05)。观察组治疗有效率明显高于对照组(P<0.05)。两组不良反应发生率比较差异有统计学意义(P<0.05)。结论:应用中药联合沙利度胺治疗MM疗效显著,可减轻化疗的不良反应,是治疗MM的理想辅助方案。
Objective: To investigate the clinical efficacy of traditional Chinese medicine combined with thalidomide in the treatment of multiple myeloma (MM). Methods: A total of 98 patients with MM were selected and randomly divided into control group (n = 49, conventional VAD chemotherapy) and observation group (n = 49) Degree amine), compare the two groups treatment effect. Results: The improvement of bone pain score and tumor burden in observation group was significantly better than that in control group (P <0.05). The observation group treatment efficiency was significantly higher than the control group (P <0.05). There was significant difference in the incidence of adverse reactions between the two groups (P <0.05). Conclusion: The application of Chinese medicine combined with thalidomide treatment of MM significant effect, can reduce the adverse reactions of chemotherapy is an ideal adjuvant treatment of MM.