慢性肝炎是指病程超过6个月的肝炎,根据病理可分成慢性持续性肝炎及慢性活动性肝炎两种。前者预后良好,不进展;后者多较严重,常发展为肝硬化。近2～3年,关于乙型肝炎发展为慢性肝炎的认识有所增加。本文从临床、生化、肝组织学及免疫学等方面,提出以下几点作为认识急性乙型肝炎发展为慢性活动性肝炎的重要征象。 Chronic hepatitis is more than 6 months duration of hepatitis, according to the pathology can be divided into chronic persistent hepatitis and chronic active hepatitis two. The former prognosis is good, no progress; the latter more serious, often develop cirrhosis. In the recent 2-3 years, there has been an increase in the understanding that hepatitis B develops into chronic hepatitis. In this paper, clinical, biochemical, liver histology and immunology, the following points as an understanding of the development of acute hepatitis B is an important sign of chronic active hepatitis.