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目的:观察肿瘤化疗对促红细胞生成素的影响。方法:分别测定健康人对照组和肿瘤患者化疗前、化疗3个周期、化疗4个周期血清促红细胞生成素及相应的血红蛋白。结果:肿瘤患者化疗前血清促红细胞生成素明显高于健康对照组;化疗3个周期、化疗4个周期血清促红细胞生成素与化疗前相比无显著性差异。结论:肿瘤患者血清促红细胞生成素是升高的,且促红细胞生成素水平不受化疗及化疗周期长短的影响。
Objective: To observe the effect of tumor chemotherapy on erythropoietin. Methods: Serum erythropoietin and corresponding hemoglobin were measured in control subjects and cancer patients before chemotherapy, 3 cycles of chemotherapy, and 4 cycles of chemotherapy. Results: Serum erythropoietin levels before chemotherapy were significantly higher in cancer patients than in healthy controls; there were no significant differences between serum erythropoietin before chemotherapy and 3 cycles of chemotherapy and 4 cycles of chemotherapy. CONCLUSIONS: Serum erythropoietin levels are elevated in cancer patients, and erythropoietin levels are not affected by the length of chemotherapy and chemotherapy cycles.