Brosimacutins H和I是从巴西的Brosimum acutifolium Huber树皮中分离出的两个具有相似结构的黄酮类化合物.此树皮被巴西当地居民作为抗发炎和抗风湿的药物,并且这两种化合物具有一定的细胞活性.以廉价的羟苯乙酮和羟苯甲醛为原料完成了黄酮化合物Brosimacutins H和I的对映选择性合成.所有新化合物的结构都经过NMR,HRMS确认. Brosimacutins H and I are two flavonoids with similar structures isolated from the bark of the Brosimum acutifolium Huber bark in Brazil, used by local residents in Brazil as anti-inflammatory and anti-rheumatic drugs and both of these compounds have certain The enzymatic activity of the flavone Brosimacutins H and I was achieved using cheap hydroxyacetophenone and hydroxybenzaldehyde as starting materials.The structures of all new compounds were confirmed by NMR and HRMS.