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目的:探讨导管化疗栓塞联合放疗治疗中晚期宫颈癌的临床应用价值。方法:选取我院中晚期宫颈癌患者120例,根据治疗方法的不同将120例中晚期宫颈癌患者分为联合组(60例)和放疗组(60例),联合组使用导管化疗栓塞联合放疗的方法进行治疗,放疗组仅使用放疗的方法进行治疗,对联合组和放疗组的近期、远期以及是否有并发症等指标进行评价,比较联合组和放疗组治疗中晚期宫颈癌的效果和差异。结果:联合组和放疗组的患者经过治疗后宫颈癌的瘤体都有一定程度的缩小,在近期缓解率方面,放疗组71.67%小于联合组90.00%,两组间差异明显(P<0.05)有统计学意义;联合治疗的方法可以有效的改善中晚期宫颈癌患者的贫血情况,手术前和手术后患者血红蛋白的水平有明显的差异;对中晚期宫颈癌患者进行三年的随访调查,在生存率方面,联合组高于放疗组,在肿瘤复发转移率方面,联合组低于放疗组;近期并发症主要包括消化道反应、骨髓抑制以及肝脏、肾脏病毒等不良反应,患者经过临床治疗并发症均得到缓解;远期并发症主要有放射性皮炎、膀胱炎以及直肠炎等,联合组出现远期并发症的几率低于放疗组。结论:对中晚期宫颈癌患者使用导管化疗栓塞联合放疗的治疗方法提高了患者近远期治疗的疗效,对患者的临床症状有所改善并且减少并发症的发生,提高患者生活质量。
Objective: To investigate the clinical value of catheterized chemoembolization combined with radiotherapy in the treatment of advanced cervical cancer. Methods: One hundred and twenty patients with advanced cervical cancer in our hospital were enrolled. According to the different treatment methods, 120 patients with advanced cervical cancer were divided into combined group (60 cases) and radiotherapy group (60 cases). The combined group was treated with catheterized chemoembolization combined with radiotherapy The radiotherapy group was treated with radiotherapy only. The combined group and radiotherapy group were evaluated for the short-term, long-term, and whether there were any complications. The effects of combination therapy and radiotherapy on advanced cervical cancer were compared with difference. Results: The tumor size of cervical cancer in the combined group and radiotherapy group was reduced to a certain extent after treatment, and 71.67% in radiotherapy group was less than 90.00% in the radiotherapy group in the short term, the difference was significant (P <0.05) There is statistical significance; the combination therapy can effectively improve the anemia in patients with advanced cervical cancer, before and after surgery patients with hemoglobin levels were significantly different; for advanced cervical cancer patients for three years follow-up survey, in the Survival rate, the combined group was higher than the radiotherapy group, the recurrence rate of tumor recurrence, the combined group was lower than the radiotherapy group; recent complications mainly include gastrointestinal reactions, bone marrow suppression and liver, kidney virus and other adverse reactions, patients after clinical treatment of concurrent Symptoms were eased; long-term complications are mainly radioactive dermatitis, cystitis and proctitis, the combined group of long-term complications appear lower than the radiation group. Conclusion: The treatment of patients with advanced cervical cancer using catheterized chemoembolization combined with radiotherapy improves the curative effect of short-term and long-term treatment, improves the clinical symptoms and reduces the incidence of complications, and improves the quality of life of patients.