激素对慢性阻塞性肺疾病（COPD），特别是对稳定期患者的疗效仍有争议。短期激素治疗对改善COPD的气流限制及气道高反应性几乎无作用，而长期激素治疗COPD的研究报道则甚少。本文对COPD患者单独吸入布地奈德（Bu刑或联用小剂量的口服强的松龙（BUd＋Ped）进行了两年的观察，评 Hormone on chronic obstructive pulmonary disease (COPD), especially in patients with stable efficacy is still controversial. Short-term hormonal therapy has little effect on improving airflow limitation and airway hyperresponsiveness in COPD, and few studies have reported the long-term hormone treatment of COPD. In this paper, budesonide alone (bu or combined with a small dose of budesonide + budesonide) in COPD patients was observed for two years,