【摘 要】
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To the Editor: Vitiligo is not a fatal disease; however, it can have strong social and psychological impacts on the patients. Genetic susceptibility, autoimmuni
【机 构】
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Department of Dermatology, The First Affiliated Hospital of China Medical University, Shenyang, Liao
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To the Editor: Vitiligo is not a fatal disease; however, it can have strong social and psychological impacts on the patients. Genetic susceptibility, autoimmunity, neural dysregulation, melanin self-destruction, and oxidative stress may be involved in the pathogenesis of vitiligo.Based on its clinical development, vitiligo can be divided into the progressive vitiligo (PV) or the stable vitiligo (SV).To date, at least 50 susceptible genes had been found in vitiligo.[1] However, only a few genes presented a clear association with the high inherent risk of vitiligo and the protein levels of these genes were scarce.
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