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目的:探讨肺通气功能中的各项指标应用于慢性阻塞性肺疾病(COPD)的诊断效果。方法:选取2009年1月～2010年1月来我院就诊的被确诊为COPD的患者100例,以回顾性分析的方式对其肺通气功能中的各项指标进行分析。结果:COPD不同程度患者的各项指标同对照组相比,有一定程度的降低(P<0.001);COPD各组间一秒量(FEV1),全部具有统计学差异(P<0.001);COPD轻度患者25%呼气流速(V25)、50%呼气流速(V50)、最大呼气中期流速(MMEF)同对照组比较有显著降低(P<0.001);除轻度外,其他三种程度COPD患者的肺活量(VC)同其他组比较,下降非常明显(P<0.001);每组的最大分钟通气量(MVV)、一秒量以及呼气峰流速度(PEF)都具有较强的正相关性。结论:肺通气功能已经成为COPD诊断中的重要标准,其中,V25、V50和MMEF为COPD诊断的敏感性指标,而MVV、PEF和FEV1则是判断COPD气流阻塞程度的相关指标。
Objective: To investigate the diagnostic value of various indexes of pulmonary ventilation in chronic obstructive pulmonary disease (COPD). Methods: A total of 100 patients diagnosed as COPD from January 2009 to January 2010 were retrospectively analyzed. The indexes of pulmonary ventilation were analyzed. Results: The indexes of patients with different degrees of COPD were lower than those of the control group (P <0.001), the one second volume (FEV1) of COPD between groups was statistically significant (P <0.001) Mild patients 25% expiratory flow (V25), 50% expiratory flow (V50), the maximum expiratory flow rate (MMEF) compared with the control group were significantly lower (P <0.001); except mild, the other three The level of vital capacity (VC) in patients with COPD was significantly lower than that in other groups (P <0.001). The MVV, one second volume and peak expiratory flow rate (PEF) Positive correlation. Conclusions: Pulmonary ventilation has become an important criterion in the diagnosis of COPD. Among them, V25, V50 and MMEF are the sensitive indexes for the diagnosis of COPD, while MVV, PEF and FEV1 are the related indexes to judge the obstruction of COPD.