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目的:探讨口腔颌面部炎性肌纤维母细胞瘤的病因、临床表现、鉴别诊断和治疗。方法:回顾分析中国医科大学附属口腔医院1990-2011年收治的21例炎性肌纤维母细胞瘤(包括炎性肌纤维母细胞瘤的其他名称)的临床资料,总结其临床症状、病灶区的影像学表现、病理学表现、临床治疗方案以及术后随访情况。结果:21例病例均在病灶边界外0.5～1 cm切除病灶。10例随访5 a以上,6例随访3 a,3例随访2 a,其中3例复发。对于复发病例,采用低剂量分次放射治疗。1例随访3 a,肿物明显减小,1例随访2 a,肿物基本消失,1例随访半年,无明显变化。结论:口腔颌面部炎性肌纤维母细胞瘤确诊依赖组织病理学表现,其中手术治疗为首选治疗方法。若入路困难或者多次复发,可辅助放射或激素治疗。
Objective: To investigate the etiology, clinical manifestations, differential diagnosis and treatment of oral and maxillofacial inflammatory myofibroblastic tumor. Methods: The clinical data of 21 cases of inflammatory myofibroblastoma (including other names of inflammatory myoblastoma) admitted to the Stomatological Hospital Affiliated to China Medical University from 1990 to 2011 were retrospectively analyzed. The clinical symptoms, the imaging of the lesion area Performance, pathology, clinical treatment plan and follow-up situation. Results: All the 21 cases were resected from 0.5 ~ 1 cm beyond the border of the lesion. Ten cases were followed up for more than 5 years, 6 cases were followed up for 3 years and 3 cases were followed up for 2 years. Three of them were relapsed. For relapse cases, the use of low-dose radiation therapy. One case of follow-up 3 a, the tumor was significantly reduced, 1 case of follow-up 2 a, the tumor disappeared, a case of follow-up for six months, no significant change. Conclusions: Oral and maxillofacial inflammatory myofibroblastic tumors are diagnosed as histopathologically confirmed, of which surgical treatment is the preferred treatment. If the difficulty of admission or multiple recurrence, may assist in radiation or hormone therapy.