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目的:观察宫颈环形电切术(LEEP)用于治疗宫颈上皮内瘤变(CIN)Ⅲ的临床疗效。方法:2008年4月～2009年4月采用LEEP对CINⅢ进行治疗,并与同期冷刀宫颈锥切术(CKC)治疗进行对比观察。结果:LEEP组手术时间和术中出血量均明显少于CKC组,两组比较差异有统计学意义(P<0.05),而LEEP组在治愈时间方面与CKC组比较差异无统计学意义(P>0.05)。LEEP组在治愈、术后出血、术后宫颈狭窄、手术残留、持续存在及复发方面与CKC组比较差异无统计学意义(P>0.05)。结论:LEEP是治疗CIN Ⅲ的有效方法,与CKC比较,其具有手术时间短、术中出血量小等优点。
Objective: To observe the clinical effect of cervical ring electrosurgical excision (LEEP) in the treatment of cervical intraepithelial neoplasia (CIN) Ⅲ. Methods: CIN Ⅲ was treated with LEEP from April 2008 to April 2009, and compared with CKC treatment in the same period. Results: The operation time and intraoperative blood loss in LEEP group were significantly less than those in CKC group (P <0.05), while there was no significant difference between LEEP group and CKC group (P > 0.05). There was no significant difference between LEEP group and CKC group in the cure, postoperative bleeding, postoperative cervical stenosis, surgical residual, persistence and recurrence (P> 0.05). Conclusion: LEEP is an effective method for the treatment of CIN Ⅲ. Compared with CKC, LEEP has the advantages of short operation time and small intraoperative blood loss.