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目的探讨不同交通路口尾气污染对学龄儿童免疫功能的影响。方法选取重交通污染区小学(A校)、轻交通污染区小学(B校),采用整群抽样的方法抽取五、六年级的学生142名,计数外周血细胞(白细胞、淋巴细胞、中间细胞、红细胞、血小板)、T淋巴细胞亚群(CD3+、CD4+、CD8+百分含量、CD4+/CD8+比值)、唾液溶菌酶含量和血清免疫球蛋白含量。结果A校小学生外周血细胞(白细胞、淋巴细胞、中性细胞、红细胞、血小板)均高于B校,除中间细胞外,差异均有显著性(P<0.05);A校小学生的唾液溶菌酶、免疫球蛋白(IgG)、T淋巴细胞亚群(CD3+、CD4+百分含量、CD4+/CD8+比值)均低于B校(P<0.05)。结论太原市不同路口尾气污染对学龄儿童的非特异性免疫、细胞免疫功能有抑制作用,对细胞和体液免疫有一定的影响。
Objective To investigate the effects of exhaust pollution at different junctions on the immune function of school-age children. Methods Primary school (A school) and light traffic polluted district primary school (B school) of heavy traffic pollution area were selected. 142 students in grade five and six were sampled by cluster sampling method, and the peripheral blood cells (leucocytes, lymphocytes, Erythrocytes, platelets), T lymphocyte subsets (CD3 +, CD4 +, CD8 + percentage, CD4 + / CD8 + ratio), salivary lysozyme content and serum immunoglobulin content. Results A group of pupils in peripheral blood cells (leukocytes, lymphocytes, neutrophils, erythrocytes, platelets) were higher than the B school, except for the intermediate cells, the difference was significant (P <0.05); A school pups saliva lysozyme, Immunoglobulin (IgG) and T lymphocyte subsets (CD3 +, CD4 +, CD4 + / CD8 + ratio) were lower than those in B school (P <0.05). Conclusion Tail gas pollution at different junctions in Taiyuan can inhibit the nonspecific immunity and cellular immunity of school-age children, and have some effects on cell and humoral immunity.