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流行性出血热患者250例,随机双盲分为病毒唑治疗组(132例)和安慰剂组(118例)。治疗7天(一个疗程)。结果治疗组血浆纤维结合蛋白较安慰剂组升高,其中轻型和危重型在两组间无显著性差异,而中、重型有显著性差异(P<0.05～0.01)。而血浆Ⅷ相关抗原及白细胞在治疗组升高不明显。
Two hundred and fifty patients with epidemic hemorrhagic fever were randomly divided into two groups: ribavirin (n = 132) and placebo (n = 118). Treatment for 7 days (one course of treatment). Results The plasma fibronectin in treatment group was higher than that in placebo group. There was no significant difference between mild group and critical group in the two groups, but there was significant difference between the two groups (P <0.05 ~ 0.01). The plasma Ⅷ-related antigens and leukocytes in the treatment group did not increase significantly.