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目的:为探讨临床病理学因素与前上纵隔淋巴结转移的相关性,从而进一步探讨甲状腺癌颈淋巴结清扫手术中同期前上纵隔淋巴结清扫的临床意义。方法:纳入54例甲状腺乳头状癌患者,在做颈淋巴结清扫的过程中,同时行前上纵隔淋巴结清扫取样进行临床研究,比较其与性别、年龄、肿瘤的大小、多灶性、有无甲状腺外侵犯、有无淋巴血管侵犯,第6区淋巴结转移情况等临床病理因素的相关性。结果:甲状腺乳头状癌患者的甲状腺肿瘤直径>4 cm、肿瘤有血管淋巴侵犯、6区淋巴结转移>3个,与前上纵隔淋巴结转移有关(P<0.05),而与性别、年龄、多灶性、有无甲状腺外侵犯无关(P>0.05)。结论:临床病理学因素与前上纵隔淋巴结转移具有关,甲状腺癌颈淋巴结清扫手术中同期前上纵隔淋巴结清扫对治疗甲状腺乳头状癌具有一定的临床意义。
Objective: To investigate the relationship between clinicopathological features and anterior mediastinal lymph node metastasis, so as to further explore the clinical significance of anterior mediastinal lymph node dissection in cervical lymph node dissection during thyroid cancer. Methods: Fifty-four patients with thyroid papillary carcinoma were enrolled in this study. In the course of cervical lymph node dissection, we performed a clinical study on the anterior mediastinal lymph node dissection and compared them with gender, age, tumor size, multifocality, thyroid External invasion, with or without lymphatic vascular invasion, lymph node metastasis in section 6 and other clinical and pathological factors. Results: Thyroid tumors in thyroid papillary thyroid carcinoma were more than 4 cm in diameter, with vascular invasion and 6 with lymph node metastasis in 3 (P <0.05), but not with gender, age, multifocality Sex, with or without extranodal involvement (P> 0.05). CONCLUSION: The clinicopathologic factors are related to the anterior mediastinal lymph node metastasis. The anterior dissecting lymph node dissection during the same period of cervical lymph node dissection in thyroid cancer has some clinical significance for the treatment of papillary thyroid carcinoma.