婴儿痉挛(infantile spasms,IS)又称West综合征,临床上以反复痉挛发作、脑电图高度失律、明显的精神运动发育落后为特征,是婴儿时期特有的癫痫综合征,属于特殊的年龄依赖性癫痫性脑病。一般认为,IS属于严重难治性癫痫范畴,分为症状性和隐源性两类,估计每年全球有2万~5万新发病例[1]。尽管很多IS属于难治性癫痫,但只要通 Infantile spasms (IS), also known as West syndrome, is clinically characterized by recurrent spasms, abnormal EEG and obvious mental retardation. It is a special epilepsy syndrome in infancy and belongs to a special age Dependent epileptic encephalopathy. Is generally believed that, IS is a serious refractory epilepsy category, divided into symptomatic and cryptogenic two categories, an estimated 20,000 new cases each year around the world [1]. Although many IS are refractory epilepsy, but as long as the pass