论文部分内容阅读
本研究通过使用自己制造的大鼠流动水游泳池，对雄性大鼠进行了６周递增负荷的游泳训练，以此来探讨运动训练对大鼠垂体－性腺轴功能的影响，结果显示：与安静对照大鼠相比，训练大鼠的一般状态较差，血清睾酮水平显著降低（Ｐ＜０．０５），血清睾酮／皮质酮比值平均降低了３０％以上；而血清ＬＨ和ＦＳＨ水平未见明显变化。通过对大鼠睾丸组织ＬＨ／ＣＧ受体的测定，显示运动训练虽未引起其最大结合量的改变，却能使其解离常数显著升高（Ｐ＜０．０５）。提示此种训练可能通过降低睾丸ＬＨ／ＣＧ受体对垂体分泌ＬＨ的亲和力，从而影响睾酮的合成。
In this study, we used a self-made rat water swimming pool to conduct 6-week swimming training with increasing load on male rats to explore the effect of exercise training on the function of the pituitary-gonadal axis in rats. The results showed that compared with the quiet control Compared with the control group, the general condition of training rats was poor, serum testosterone level was significantly decreased (P <0.05), serum testosterone / corticosterone ratio was reduced by more than 30% on average; while serum LH and FSH levels did not change significantly . The test of LH / CG receptor in rat testis showed that although exercise training did not cause the change of maximal binding, the dissociation constant of LH / CG receptor increased significantly (P <0.05). Suggesting that such training may affect the testosterone synthesis by reducing testosterone LH / CG receptor secretion of pituitary LH affinity.