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目的:观察窄谱中波紫外线与更昔洛韦联合应用治疗带状疱疹后遗神经痛的临床疗效。方法:将怀集县人民医院2014年8月至2016年6月收治的56例带状疱疹后遗神经痛患者随机分为联合组和对照组,予以对照组患者更昔洛韦治疗,予以联合组患者窄谱中波紫外线联合更昔洛韦治疗。结果:联合组患者的疼痛开始缓解时间为(1.32±0.36)d,早于对照组患者的(1.98±0.41)d。治疗前两组患者的疼痛视觉模拟评分法(VAS)评分比较,差异无统计学意义(P>0.05),治疗后2周、4周联合组患者的VAS评分均低于对照组患者,差异具有统计学意义(P<0.05)。联合组患者的疾病治疗总有效率为92.86%,较对照组患者的71.43%高,差异具有统计学意义(P<0.05)。结论:窄谱中波紫外线与更昔洛韦联合应用治疗带状疱疹后遗神经痛,可获得可靠疗效。
Objective: To observe the clinical efficacy of narrow-band UVB combined with ganciclovir in the treatment of postherpetic neuralgia. Methods: Huaiji County People’s Hospital from August 2014 to June 2016 admitted 56 cases of postherpetic neuralgia patients were randomly divided into the combined group and the control group, the control group patients with ganciclovir treatment, to be combined The patients were treated with narrow band ultraviolet B combined with ganciclovir. Results: The pain relief time in the combined group was (1.32 ± 0.36) d, earlier than that in the control group (1.98 ± 0.41) d. There was no significant difference in VAS scores between the two groups before treatment (P> 0.05). The VAS scores of the combined group at 2 weeks and 4 weeks after treatment were lower than those in the control group, the differences were statistically significant Statistical significance (P <0.05). The total effective rate of disease treatment in combination group was 92.86%, which was higher than that in control group (71.43%), the difference was statistically significant (P <0.05). Conclusion: The combination of narrow-band UVB and ganciclovir for the treatment of postherpetic neuralgia may achieve reliable results.