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[目的]探讨燕麦β-葡聚糖联合Vit-C对高脂血症大鼠降血脂降体重作用。[方法]将雄性SD大鼠造成高脂模型,然后按体重随机分为7组,分别喂饲高脂饲料、基础饲料及在高脂实验组加不同剂量的β-葡聚糖及Vit-C共5周。于实验末心脏取血,测定血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、动脉硬化指数(AI),判定其对血脂的影响;测定体重、脂肪含量、肥胖指数(Lee’index),判定其对体重的影响。[结果]燕麦β-葡聚糖联合Vit-C能够降低TC、TG、LDL-C、AI的水平,升高HDL-C的水平;并能够降低大鼠体重、脂肪含量以及肥胖指数。[结论]燕麦β-葡聚糖联合Vit-C具有一定的降血脂、降体重作用。
[Objective] To investigate the effect of oat β-glucan combined with Vit-C on the blood lipid levels in hyperlipidemic rats. [Method] Male SD rats were induced to develop a model of hyperlipidemia and then randomly divided into 7 groups according to body weight. The rats were fed with high fat diet, basic diet and high fat diet with different doses of β-glucan and Vit-C A total of 5 weeks. At the end of the experiment, blood was taken from the heart to measure the levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), arteriosclerosis index (AI) , To determine its impact on blood lipids; determination of body weight, fat content, fat index (Lee’index), to determine its impact on body weight. [Result] Oat β-glucan combined with Vit-C could reduce the levels of TC, TG, LDL-C and AI and increase the level of HDL-C, and also reduce body weight, fat content and obesity index in rats. [Conclusion] oat β-glucan in combination with Vit-C has the effect of lowering blood fat and reducing body weight.