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目的观察中西医联合治疗类风湿关节炎(RA)的疗效和药物不良反应。方法将类风湿患者60例,随机分为两组,治疗组30例,口服祛风活血汤和甲氨蝶呤(MTX);对照组30例口服MTX。结果祛风活血汤和MTX联合治疗RA疗效显著。祛风活血汤联合MTX和MTX治疗RA均可明显减轻关节肿胀、疼痛,改善关节功能,降低炎性指标(P<0.05)。结论祛风活血汤+MTX联合治疗RA不仅具有抗炎镇痛、调节免疫反应的作用,且起效快,较安全。
Objective To observe the curative effect and adverse drug reaction of combined treatment of traditional Chinese and western medicine on rheumatoid arthritis (RA). Methods Sixty patients with rheumatoid arthritis were randomly divided into two groups. The treatment group was treated with Qufeng Huoxue Decoction and methotrexate (MTX) orally. Thirty patients in the control group were given oral MTX. Results Qufeng Huoxue Decoction and MTX combined treatment of RA significant effect. Qufeng Huoxue decoction combined with MTX and MTX can significantly reduce joint swelling and pain, improve joint function and reduce inflammatory index (P <0.05). Conclusion Qufeng Huoxue Decoction + MTX combined with RA not only has anti-inflammatory and analgesic effects, but also has the effect of modulating the immune response and has the quick onset and safety.