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氟喹诺酮类抗菌药物是临床常用的人工合成抗菌药物,由于该药应用的日益广泛和新型药物不断研发,该类药物毒性新发现及报道增多,对毒性的发生及机制研究也逐渐深入,现在受到研究者的更多关注。总结和概述近年来对氟喹诺酮类药物不良反应及机制研究领域的进展。介绍临床较多见的不良反应及其机制。这将为临床合理使用氟喹诺酮类药物提供更多的科学依据。
Fluoroquinolones antibacterials are commonly used synthetic antimicrobial drugs. Due to the increasingly wide application of this drug and the continuous development of new drugs, new discoveries and reports on the toxicity of these drugs have been reported. The research on the occurrence and mechanism of toxicity has also been gradually deepened. Now, Researchers pay more attention. In this paper, we summarize and summarize the progress in the field of adverse reactions and mechanisms of fluoroquinolones in recent years. Introduction of clinical more common adverse reactions and their mechanisms. This will provide more scientific basis for clinical rational use of fluoroquinolones.