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目的：对肿瘤化疗患者外周中心静脉（PICC ）置管的并发症及造成这种并发症的相关因素进行分析，为减少和预防并发症的发生提供理论依据。方法以2011年3月至2014年9月来该院进行肿瘤化疗的127例化疗并行PICC置管的患者为研究对象，对其发生的并发症及导致并发症发生的相关因素进行分析。结果127例行PICC置管患者中，17例患者发生机械性静脉炎，发生率13．38％，8例发生导管相关性感染，发生率为6．29％，7例发生导管堵塞，发生率5．51％；头臂静脉PICC置管静脉炎的发生率为60．00％，明显高于贵要静脉2．41％和正中静脉20．70％，差异有统计学意义（P＜0．05）；常规护理维护模式导管相关性感染的发生率为11．11％，明显高于3M换药模式护理1．56％，差异有统计学意义（P＜0．05）。结论肿瘤化疗患者进行 PICC置管治疗容易产生并发症，而正确的穿刺方法、选择合适的穿刺部位及采取有效的护理能够减少机械性静脉炎、导管相关性感染及导管堵塞等并发症的发生。“,”Objective To analyze the peripherally inserted central catheter(PICC) catheter complications and their related factors causing these complications in the tumor patients with chemotherapy to provide the theoretic ba‐sis for reducing and preventing the occurrence of these complications .Methods 127 cases of tumor chemotherapy and PICC in our hospital from March 2011 to September 2014 catheter patients were taken as the research subjects .The complications and the related factors causing the complications were analyzed .Results Among 127 cases of PICC ,17 cases of mechanical phlebitis occurred with the incidence rate of 13 .38% ,8 cases of catheter related infections oc‐curred with the incidence rate of 6 .29% and 7 cases of catheter blockage with the incidence rate of 5 .51% ;the PICC catheter phlebitis incidence rate in brachiocephalic vein was 60 .00% ,which was significantly higher than 2 .41% in basilic vein and 20 .70% in the median vein ,the differences were statistically significant (P<0 .05);the incidence rate of catheter related infections in the routine nursing maintenance mode was 11 .11% ,which was obviously higher than 1 .56% in the 3M dressing mode of nursing ,the difference was statistically significant (P<0 .05) .Conclusion The patients with tumor chemotherapy by PICC are prone to generate complications ,and the correct puncture method ,se‐lecting suitable puncture site and taking effective nursing care can reduce the complications of mechanical phlebitis , catheter related infection and catheter blockage .