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目的探讨胃癌手术患者预后的影响因素。方法选取我院2006至2010年收治的临床资料完整的63例胃癌术后患者,最低随访3年,对年龄(≤60岁和>60岁)、性别、部位(胃底、胃体和胃窦)、病理类型(腺癌、黏液癌和其他)、第七版TNM分期方法(Ⅰ期、Ⅱ期、Ⅲ期和Ⅳ期)、手术方式(根治切除术和姑息手术)、是否化疗和有无并发症等临床资料对预后影响进行统计学分析。结果全组总体平均生存期40.1个月,中位生存期29个月。单因素分析显示胃癌Ⅰ~Ⅳ分期(第七版TNM分期方法)、手术方式(根治手术和姑息手术)、术后有无并发症与生存期相关(P<0.05)。Cox回归模型多因素分析提示临床分期和术后是否有并发症是生存时间最为有力的影响因素(P<0.05)。结论临床分期(第七版TNM分期方法)和术后是否有并发症是影响胃癌预后的独立因素。
Objective To investigate the influencing factors of prognosis in gastric cancer patients. Methods Sixty-three patients with postoperative gastric cancer with complete clinical data from 2006 to 2010 in our hospital were recruited. The patients were followed up for 3 years with the lowest follow-up, and their age (≤60 and ≥60 years), gender, location (stomach fundus, gastric body and gastric antrum ), Pathological types (adenocarcinoma, mucinous carcinoma and others), the seventh edition of the TNM staging method (stages I, II, III and IV), surgical modality (radical resection and palliative surgery), chemotherapy and presence Complications and other clinical data on the prognosis of the statistical analysis. Results The overall average overall survival of 40.1 months, the median survival of 29 months. Univariate analysis showed that stage Ⅰ ~ Ⅳ staging of gastric cancer (the seventh edition of TNM staging), surgical methods (radical surgery and palliative surgery), postoperative complications and survival related (P <0.05). Cox regression model multivariate analysis showed that the clinical stage and postoperative complications were the most significant influencing factors of survival time (P <0.05). Conclusion The clinical stage (seventh edition of TNM staging) and postoperative complications are independent prognostic factors of gastric cancer.