随着原子能事业的发展,接触铀化合物的工人日趋增多。研究铀致机体损伤是辐射防护的重要课题之一。 铀是对肾脏有选择性毒性的剧毒物质,观察早期肾功能损害具有重要临床意义。有关铀中毒的资料,国外文献较多,国内资料少见。尤其用狗为实验对象的资料更属贫乏。从生理生态观点来看,取得狗的实验资料,对于研究人的铀致损伤效应是有意义的。 With the development of atomic energy, the number of workers exposed to uranium compounds is on the rise. Study of uranium-induced body damage is one of the important issues of radiation protection. Uranium is a highly toxic substance that is selectively toxic to the kidneys. It is of great clinical significance to observe early renal impairment. Uranium poisoning information, more foreign literature, domestic information rare. In particular, the data used as the experimental subject is even more poor. From a physical and ecological point of view, obtaining experimental data from dogs makes sense for studying human uranium-induced injury effects.