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一些针对不同人群的研究提示:夜间血压是一个较白天血压更强的心血管事件预测因子,针对夜间高血压的治疗策略已经成为关注的焦点。该研究旨在探讨改变降压药服用时间对2型糖尿病患者降压疗效的影响。该研究是一个开放交叉研究,包括2型糖尿病合并夜间高血压[夜间收缩压>120mm Hg(1mm Hg=0.133kPa)]患者41例。患者随机分为早晨或夜间服用降压药8周,1次/d,然后改变服药时间治疗8周。
Some studies targeting different populations suggest that nocturnal BP is a more predictive cardiovascular event than daytime BP, and treatment strategies for nocturnal hypertension have become the focus of attention. The aim of this study was to investigate the effect of varying the duration of antihypertensive medication on antihypertensive efficacy in patients with type 2 diabetes. The study was an open cross-over study involving 41 patients with type 2 diabetes with nocturnal hypertension [nighttime systolic blood pressure> 120 mm Hg (1 mm Hg = 0.133 kPa)]. Patients were randomly divided into morning or night taking antihypertensive drugs for 8 weeks, 1 time / d, and then change the medication time for 8 weeks.