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纤维粘连蛋白(fibronectin,FN)及层粘连蛋白(laminin,LN)是近年来受到广泛重视的细胞外基质非胶原糖蛋白。FN主要由中胚层来的细胞产生,亦可由上皮细胞及内皮细胞生成;LN则主要由上皮细胞及内皮细胞合成。FN以可溶及不溶两种形式分别存在于各种体液及细胞外基质(包括某些基膜);LN则以不溶的形式
Fibronectin (FN) and laminin (LN) are extracellular matrix non-collagen glycoproteins that have received much attention in recent years. FN is mainly produced by mesoderm cells, but also by epithelial cells and endothelial cells; LN is mainly synthesized by epithelial cells and endothelial cells. FN exists in both soluble and insoluble forms in various body fluids and extracellular matrix (including some basement membranes); LN is insoluble