新近的资料提示,Edmoaston-Zagreb麻疹疫苗对幼婴的免疫原性比Schwarz麻疹疫苗高,但是有几个研究小组所用的Edmons-ton-Zagreb麻疹疫苗剂量高于常规用量,由此提出一个问题,即该疫苗的高免疫原性是否与疫苗株或剂量有关,为此,作者进行了Edmonston-Zagreb和Schwarz麻疹疫苗免疫婴儿的随机、双盲比较试验。将入选的无麻疹病史、两周内未接种麻疹疫苗或口服脊髓灰质炎疫苗、无免疫损害或严重营养不良的研究对象分为9组:7组 Recent data suggest that the Edmaston-Zagreb measles vaccine is more immunogenic for infants than the Schwarz measles vaccine but there are several groups that used Edmons-ton-Zagreb measles vaccine at a higher than usual dose, raising the question of whether, Ie whether the high immunogenicity of the vaccine is related to the vaccine strain or dose, for which the author conducted a randomized, double-blind, comparative trial of infants immunized with Edmonston-Zagreb and Schwarz measles vaccine. Participants who were enrolled in the study without a history of measles, those who had not been vaccinated against measles or oral polio within two weeks, were immunocompromised, or severely malnourished were divided into nine groups: Group 7