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目的探讨单腔中心静脉导管用于恶性胸腔积液引流及腔内灌注化疗药物的临床应用价值。方法对45例胸腔积液的患者行胸腔内留置单腔静脉导管;间断引流胸腔积液及腔内灌注顺铂药物;给予止吐等对症支持治疗,预防化疗药物的毒副反应。结果本组45例,CR17例(37.8%),PR21例(46.7%),PD5例(11.1%),NC2例(4.4%),总有效率(CR+PR)为84.4%。结论采用中心静脉导管置管行胸腔引流具有创伤小、安全性高、引流效果好、用药方便等优点,在临床有推广价值。
Objective To investigate the clinical value of single-lumen central venous catheter for the treatment of malignant pleural effusion and intracavitary chemotherapy. Methods Forty-five patients with pleural effusion underwent single vena cava catheterization in the thoracic cavity. Intermittent drainage of pleural effusion and intraluminal infusion of cisplatin drugs were given symptomatic and antiemetic supportive therapy to prevent the side effects of chemotherapeutic drugs. Results The total 45 patients were CR17 (37.8%), PR21 (46.7%), PD5 (11.1%) and NC2 (4.4%). The total effective rate (CR + PR) was 84.4%. Conclusion The central venous catheterization of chest drainage with less trauma, high safety, drainage effect is good, convenient medication, etc., in the clinical promotion value.