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目的探讨急性后极部多灶性鳞状色素上皮病变（ａｃｕｔｅｐｏｓｔｅｒｉｏｒｍｕｌｔｉｆｏｃａｌｐｌａｃｏｉｄｐｉｇｍｅｎｔｅｐｉｔｈｅｌｉｏｐａｔｈｙ，ＡＰＭＰＰＥ）的发病机制及病变的变化规律。方法用眼底荧光血管造影（ｆｕｎｄｕｓｆｌｕｏｒｅｓｃｅｉｎａｎｇｉｏｇｒａｐｈｙ，ＦＦＡ）和吲哚青绿血管造影检查（ｉｎｄｏｃｙａｎｉｎｅｇｒｅｅｎａｎｇｉｏｇｒａｐｈｙ，ＩＣＧＡ）观察本病的改变，共６例（８只眼），其中１例观察１６０天。结果①ＦＦＡ：３只眼急性病变病灶早期为弱荧光，以后着染荧光。５只眼陈旧病灶为色素上皮脱色素的窗样缺损及色素沉着的遮蔽荧光；②ＩＣＧＡ：３只眼急性期病变呈斑片状充盈缺损，４只眼陈旧病灶弱荧光斑未见恢复，１只眼无异常表现。结论本病变发病为脉络膜毛细血管阻塞，继发的视网膜色素上皮改变可能为脉络膜炎性病变所致
Objective To investigate the pathogenesis and pathological changes of acute posterior multifocal plaginal pigment epithelial lesions (APMPPE). Methods Six patients (8 eyes) were observed by fundus fluorescein angiography (FFA) and indocyaninegreenangiography (ICGA). One case was observed for 160 days. Results (1) FFA: The lesions of acute lesions in 3 eyes were weakly fluorescent at early stage, and then stained with fluorescence. Five eyes of old lesions were window-like defect of pigment epithelium depigmenting and pigmented occlusion fluorescence. ②ICGA: The acute lesion of 3 eyes showed patchy filling defects, and the weak spots of 4 old eyes showed no signs of recovery. No abnormal eye performance. Conclusion The incidence of this disease is choriocapillaris obstruction, secondary retinal pigment epithelial changes may be caused by choroidal inflammatory lesions