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微石症是指直径小于3mm的胆囊结石,通常腹部B超和常规胆囊造影难以发现。显微镜下观察到胆汁中存在晶体即可诊断微石症。对微石症的发病机制尚不甚明了。此研究旨在比较微石症与胆石症病人及健康志愿者胆固醇成核时间、胆固醇饱和指数(CSI)和胆囊收缩力的异同,同时观察熊去氧胆酸(UDCA)对微石症病人成核时间和胆汁脂质成分的影响。
Microlithiasis refers to gallbladder stones less than 3 mm in diameter, and is usually difficult to detect by abdominal ultrasonography and conventional cholecystography. Microscopic observation of the presence of crystals in the bile can diagnose microlithiasis. The pathogenesis of microlithiasis is not yet clear. The aim of this study was to compare the differences in Cholesterol Time, Cholesterol Saturation Index (CSI), and Gallbladder Contractility between patients with microlithiasis and cholelithiasis and healthy volunteers, and to observe the effect of ursodeoxycholic acid (UDCA) on patients with microlithiasis Nuclear Time and Biliary Lipid Composition.