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目的观察包皮环切术对慢性念珠菌性包皮龟头炎的疗效和预防复发的作用。方法选择有包皮过长或包茎并且患慢性念珠菌性包皮龟头炎的91例患者,按年龄随机分为两组,治疗组应用二氧化碳激光行包皮环切术。对照组予氟康唑胶囊口服,外用2%克霉唑霜治疗,连续2周,两组患者均随访3个月观察疗效。结果治疗组治愈率(93.62%)明显高于对照组治愈率(59.09%),差异有统计学意义(P<0.01)。两组患者均无特殊不良反应。结论包皮环切术对慢性念珠菌性包皮龟头炎起到了治疗和预防的作用,效果明显,同时也避免了因长期服用抗真菌药物对肝肾功能造成的损伤。
Objective To observe the curative effect of circumcision on chronic candidal foreskin balanitis and its role in preventing relapse. Methods A total of 91 patients with prepuce or phimosis who had chronic candidal foreskin balanitis were randomly divided into two groups according to their age. The patients in the treatment group were treated with CO2 laser circumcision. The control group was given oral fluconazole capsules, topical 2% clotrimazole cream treatment, continuous 2 weeks, two groups of patients were followed up for 3 months to observe the effect. Results The cure rate of the treatment group (93.62%) was significantly higher than that of the control group (59.09%), the difference was statistically significant (P <0.01). No special adverse reactions were found in both groups. Conclusions Circumcision is effective in the treatment and prevention of chronic candidal foreskin balanitis, and also avoids the damage of liver and kidney caused by long-term use of antifungal agents.