急性髓系白血病(acute myelogenous leukemia,AML)是我国最常见的恶性血液病。根据白血病细胞分化受阻的阶段不同以及细胞遗传学上的差异将AML分为各亚型。以往的观点认为,不同分化阶段的髓系细胞恶性转化导致了AML表型上的差异。但种种体外分析表明,在白血病细胞群中,并非所有 Acute myelogenous leukemia (AML) is the most common malignant hematological disease in our country. AML is divided into subtypes according to the different phases of leukemia cell differentiation and the cytogenetic differences. In the past, it was thought that the malignant transformation of myeloid cells at different stages of differentiation led to phenotypic differences in AML. However, a variety of in vitro analyzes show that not all of them are in the leukemic cell population