论文部分内容阅读
采用花环形成及花环形成阻断实验和免疫荧光染色及其阻断实验研究抗肝癌米托蒽醌免疫毫微粒 ( HAb18- DHAQ- BSA- NP)体外靶向人肝癌细胞的特性 ,并利用 3H- Td R掺入法研究其选择性靶向杀伤人肝癌细胞的作用。结果显示 ,HAb18- DHAQ- BSA- NP能有效地特异性靶向结合人肝癌细胞 ,且对人肝癌细胞具有特异性杀伤作用 ,这种杀伤作用的特异性由人肝癌单克隆抗体 HAb18决定。
Using garland formation and garland formation blocking experiments and immunofluorescence staining and blocking experiments to study the characteristics of anti-hepatoma mitoxantrone immune nanoparticles (HAb18-DHAQ-BSA- NP) targeting human hepatoma cells in vitro and using 3H- Td R incorporation assay was used to study the selective targeting of human hepatoma cells. The results showed that HAb18-DHAQ-BSA- NP can specifically and specifically bind to human hepatocellular carcinoma cells and has a specific killing effect on human hepatoma cells. The specificity of this killing effect is determined by the human liver cancer monoclonal antibody HAb18.