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[《医学世界报导》1989年5月]根据美国田纳西州首府纳什维尔的报道,用二氢麦角胺喷鼻剂治疗,可缓解偏头痛而无明显副作用或造成药物依赖性。美国巴尔的摩头痛研究所的 Brian Mondell 称,曾在先后两次发作头痛期间给病人应用二氢麦角胺喷鼻剂或安慰剂治疗。在第一次头痛发作时,44例接受二氢麦角胺喷鼻剂治疗的病人,平均头痛持续时间较用安慰荆的47例病人有明显缩短,前者为13小时,后者为20.3小时。在第二次头痛发作时,47例接受二氢麦角胺喷鼻剂治疗者的平均头痛持续时间为13.7小时,而44例接受安慰剂治疗者则为17.5小时,二者在
[Medical World Report, May 1989] According to a report in Nashville, Tenn., The capital of the state of Tennessee, treatment with dihydroergotamine nasal spray relieves migraines without significant side effects or drug dependence. Brian Mondell of the Baltimore Headache Institute in the United States states that patients had been treated with either dihydroergotamine nasal spray or placebo during two consecutive headaches. At the time of the first episode of headache, the mean headache duration was significantly shorter in 44 patients treated with dihydroergotamine nasal spray, compared with 47 patients treated with placebo, the former being 13 hours and the latter 20.3 hours. On the second episode of headache, the mean duration of headaches in 47 patients receiving di- ergotamine nasal spray was 13.7 hours, compared with 17.5 hours in 44 patients receiving placebo,