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一九八二年十月,我有机会应邀参加了二十四届日本消化器病学会的秋季大会,现根据这次大会并参照第20届日本消化器内窥镜学会、第20届日本胃集团检诊学会等有关资料,对日本消化器病的研究动态,作一简要介绍。一、实验胃癌的动物模型用实验胃癌动物模型研究胃癌的发生、发展及判定抗癌药物的疗效,已被不少学者所采用。日本国立卫生实验所用Wistar系大鼠经MNNG(methyl nitro nitrosoguanidine)水溶液喂养,可以出现高率的胃癌。此种胃癌与人的胃癌很相似,可分为分化好的与分化不良的两类。如先用药物(如JAA)或冷冻造成溃疡,以后再给MNNG,在溃疡
In October 1982, I had the opportunity to be invited to attend the Autumn Session of the 24th Japan Society of Digestive Diseases. Based on this conference and referring to the 20th Japan Digestive Endoscopy Society, the 20th Japanese stomach Group Medical Association and other relevant information on the Japanese digestive system research developments, make a brief introduction. First, the experimental animal model of gastric cancer Experimental animal model of gastric cancer study of the occurrence and development of gastric cancer and determine the efficacy of anti-cancer drugs, has been adopted by many scholars. Japan National Health Experiment Wistar rats fed MNNG (methyl nitro nitrosoguanidine) aqueous solution, can occur in a high rate of gastric cancer. Such gastric cancer and human gastric cancer are very similar, can be divided into well-differentiated and poorly differentiated two categories. If the drug (such as JAA) or frozen cause ulcers, and then give MNNG, in the ulcer